Amyloid β-Protein (1-46)

CompanySerial Number：DC160048(48)

ProductName：Amyloid β-Protein (1-46)

Synonym：

CASNo.：[285554-31-6]

Sequence(three-letter)：H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala-Thr-Val-Ile-Val-OH

Sequence(one-letter)： DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIV-OH

ConstitutionalFormula：

MolecularFormula： C223H347N59O65S

MolecularWeight：4926.63

References： G.Zhaoet al., J. Biol. Chem., 279, 50647 (2004)
G.Zhao et al., J. Biol. Chem., 280, 37689 (2005)
Y.Qi-Takahara et al., J. Neurosci., 25, 436 (2005)

Illustration：Precursorof the secreted amyloid-β-protein 1-40 and 1-42. The identification ofamyloid-β-protein 1-46 led to the identification of a zeta-cleavage sitebetween the known γ- and ε-cleavage sites within the transmembrane domain ofamyloid-β precursor protein (APP).

ConditionOf Storage: -20± 5 °C