Amyloid β-Protein (12-28)

Company Serial Number：DC160047(47)

Product Name：Amyloid  β-Protein (12-28)

Synonym： Alzheimer's Disease β-Protein (12-28)

CAS No.：[107015-83-8]

Sequence(three-letter)：H-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OH

Sequence(one-letter)： VHHQKLVFFAEDVGSNK-OH

Constitutional Formula：

Molecular Formula： C89H135N25O25

Molecular Weight：1955.2

References： J.F.Flood et al., Brain Res., 663, 271 (1994)
 M.Sadowski et al., Am. J. Pathol., 165, 937 (2004)

Illustration：Injection  of this amyloid β-protein fragment into different limbic system structures in  mice impaired retention with remarkably similar efficacy and in a  dose-dependent manner. It is suggested that this peptide and other amyloid  β-protein fragments may exert dysregulatory cognitive effects by incoordination  of K+ channel function in neurons, glia and endothelial cells.

Condition Of Storage: -20 ± 5 °C

★ 本产品仅供研发使用，不能用于人体