Propionyl-Amyloid β-Protein (31-34) amide

CompanySerial Number：DC160064(64)

ProductName：Propionyl-Amyloid β-Protein(31-34) amide

Synonym：

CASNo.：[256419-86-0]

Sequence(three-letter)：Propionyl-Ile-Ile-Gly-Leu-NH2

Sequence(one-letter)： Propionyl-IIGL-NH2

ConstitutionalFormula：

MolecularFormula： C23H43N5O5

MolecularWeight：469.63

References： G.Laskayet al., Biochem. Biophys. Res. Commun., 235, 479 (1997)

Illustration：Thisanalog is capable of blocking the long-term cellular effect of the amyloidβ-protein (1-42). It is the first report of an analog of amyloid β-proteinfragment capable of blocking one of its physiological effects, thereby raisingthe possibility that this sequence could prove to be a lead compound fordesigning effective β-amyloid antagonists. PrIIGLa protected glial and neuronalcells from the toxic effects of Aβ 1-42.

ConditionOf Storage: -20± 5 °C