(Pro18,Asp21)-Amyloid β-Protein (17-21)

Company Serial Number：DC160055(55)

Product Name：(Pro18,Asp21)-Amyloid  β-Protein (17-21)

Synonym：

CAS No.：[182912-74-9]  net

Sequence(three-letter)：H-Leu-Pro-Phe-Phe-Asp-OH Trifluoroacetate salt

Sequence(one-letter)： LPFFD-OHTrifluoroacetatesalt

Constitutional Formula：Amyloid Peptides\67.png

Molecular Formula： C33H43N5O8

Molecular Weight：637.73

References： C.Soto et al., Nat. Med., 4, 822 (1998)
 C.Yang et al., J. Mol. Model., 16, 813 (2010)
 M.H.Viet et al., J. Phys. Chem. B, 115, 7433 (2011)
 ü.Murvai et al., J. Mol. Recognit., 24, 453 (2011)

Illustration：The  pentapeptide LPFFD (iAβ5), a highly efficient β-sheet breaker, inhibited  amyloid formation in vitro, prevented amyloid neurotoxicity in cell culture,  reduced in vivo cerebral Aβ deposition and completely blocked amyloid fibril  formation in rat brain.

Condition Of Storage: -20 ± 5 °C

★ 本产品仅供研发使用，不能用于人体