(Gly22)-Amyloid β-Protein (1-40)
CompanySerial Number:DC160031(31)
ProductName:(Gly22)-Amyloid β-Protein(1-40)
Synonym: Amyloidβ-Protein (1-40) Arctic Mutation, Amyloid β-Protein (1-40) E22G
CASNo.:[175010-18-1] net
Sequence(three-letter):H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Gly-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OHTrifluoroacetate salt
Sequence(one-letter): DAEFRHDSGYEVHHQKLVFFAGDVGSNKGAIIGLMVGGVV-OHTrifluoroacetatesalt
ConstitutionalFormula:
MolecularFormula: C191H291N53O56S
MolecularWeight:
References: A.P?ivi?et al., J. Mol. Biol., 339, 145 (2004)
B.M.Whalen et al., Neurobiol. Dis., 20, 254 (2005)
N.Yamamoto et al., J. Biol. Chem., 282, 2646 (2007)
A.R.Lam et al., J. Am. Chem. Soc., 130, 17413 (2008)
R.Solito et al., Exp. Cell Res., 315, 385 (2009)
A.Jan et al., Nat. Protoc., 5, 1186 (2010)
Illustration:Thehighly neurotoxic arctic mutant (E22G) of Aβ has been used to study themechanisms underlying the formation of soluble and insoluble β-amyloidaggregates. As the wild-type Aβ, the arctic mutant preferably assembles in thepresence of GM1 ganglioside.
ConditionOf Storage: -20± 5 °C
★ 本产品仅供研发使用,不能用于人体