Amyloid β-Protein (1-28)

CompanySerial Number：DC160019(19)

ProductName：Amyloid β-Protein (1-28)

Synonym： Alzheimer'sDisease β-Protein (SP28)

CASNo.：[109770-29-8] net

Sequence(three-letter)：H-Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-OHTrifluoroacetate salt

Sequence(one-letter)： DAEFRHDSGYEVHHQKLVFFAEDVGSNK-OHTrifluoroacetatesalt

ConstitutionalFormula：

MolecularFormula： C145H209N41O46

MolecularWeight：3262.5

References： D.A.Kirschneret al., Proc. Natl. Acad. Sci. USA, 84, 6953 (1987)
J.Kang et al., Nature, 325, 733 (1987)
J.L.Marx, Science, 243, 1664 (1989)
J.S.Whitson et al., Science, 243, 1488 (1989)
M.Hollosi et al., Pept. Res., 2, 109 (1989)
D.Burdick et al., J. Biol. Chem., 267, 546 (1992)

S.-T.Liuet al., Biochemistry, 38, 9373 (1999)

Illustration：Theremarkable histochemical features of Alzheimer's disease (AD) are plaques thatcontain cores of extracellular filaments, which have been identified as amyloidsubstance. The major component of this amyloid is the β-protein. The syntheticpeptide, having the same sequence as the N-terminal 28 residues, formed fibrilsthat have the same antigenic and structural features like the native AD amyloidfilaments.

ConditionOf Storage: -20± 5 °C

★ 本产品仅供研发使用，不能用于人体