Acetyl-Amyloid β/A4 Protein Precursor770(96-110) (cyclized)
CompanySerial Number:DC160001
ProductName:Acetyl-Amyloid β/A4 ProteinPrecursor770 (96-110) (cyclized)
Synonym: Ac-APP770(96-110) (cyclized)
CASNo.:[289634-54-4]
Sequence(three-letter):Ac-Asn-Trp-Cys-Lys-Arg-Gly-Arg-Lys-Gln-Cys-Lys-Thr-His-Pro-His-NH2(Disulfide bond)
Sequence(one-letter): Ac-NWCKRGRKQCKTHPH-NH2(Disulfidebond)
ConstitutionalFormula:
MolecularFormula: C81H128N32O19S2
MolecularWeight:1918.24
References: D.H.Smallet al., J. Neurosci., 14, 2117 (1994)
Illustration:Thiscyclized peptide which is homologous to the heparin-binding domain of APP,binds strongly to heparin and inhibits binding of 125I-labeled APP to heparin(IC50= 10-7M). The peptide blocks the heparan sulfate proteoglycan-dependentstimulatory effect of APP on neurite outgrowth.
ConditionOf Storage: -20± 5 °C
★ 本产品仅供研发使用,不能用于人体